产品货号：
Z22642
中文名称：
p16INK4a/CDKN2A抗体
英文名称：
Anti-p16INK4a/CDKN2A Antibody
产品规格：
100μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-p16INK4a/CDKN2A Antibody |
| 指标别名 | ARF;ARF;CDKN2A;CDK4 inhibitor p16 INK4;CDK4 inhibitor p16INK4;CDK4I;CDKN2;CDKN2A;CMM2;INK4;INK4a;MLM;MTS 1;MTS1;Multiple tumor suppressor 1;P16;p16 INK4;p16 INK4a;p16INK4;p16INK4a;P16-INK4A;TP16 |
| 克隆性 | Polyclonal |
| 检验物种 | human |
| 应用范围 | IHC,WB |
| 基因名称 | CDKN2A |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | human p16 protein (missing the first 7 amino acids) |
| 成分 | 0.01% (w/v) Sodium Azide |
| 纯化方式 | This product was prepared from monospecific antiserum by delipidation and defibrination.Antiserum will specifically react with a p16 protein from human tissue.Cross-reactivity may occur with p15 when immunoprecipitating in vitro translated product but not in immunoblots.Potentially cross reacts with p15.5. |
| 浓度 | 85mg/mL by Refractometry |
| 产品形态 | 溶液 |
| 保存条件 | Store vial at -20℃ prior to opening.Aliquot contents and freeze at -20℃ or below for extended storage.Avoid cycles of freezing and thawing.Centrifuge product if not completely clear after standing at room temperature.This product is stable for several weeks at 4℃ as an undiluted liquid.Dilute only prior to immediate use.Expiration date is one (1) year from date of opening. |
| 背景资料 | The gene for CDK2NA generates several transcripts/proteins which differ from each other in their first exons.Three of these transcripts are generated by alternative splicing (isoform 1 a.k.a p16INK4A,isoform 2 and isoform 3 a.k.a p12),two of which are known to function as inhibitors of CDK4 kinase.One other transcript that is generated from this gene contains an alternate reading frame (ARF),with the first exon located 20kb upstream of the remainder of the gene (isoform 4 a.k.a.p14ARF,p19ARF,ARF).In spite of the structural and some functional differences,all the proteins encoded by the CDKN2A gene are involved in cell cycle G1 control. |
| Uniprot ID | P42771 |
| 推荐稀释比 | ELISA:1:5,000 - 1:20,000 IHC:1:500 IP:1:100 WB:1:500 - 1:5,000 |
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